H2 Blocker vs. Antacid vs. PPI
There are various treatment options for acid reflux and heartburn. The three main categories of products include histamine-2 blockers (H2 blockers), antacids, and proton pump inhibitors (PPIs). Learn more about each of them and remember to speak with your healthcare provider about which treatment option might be right for you.
H2 Blockers
H2 blockers are intended to treat unexpected heartburn and lower the amount of acid your stomach produces by blocking the histamine receptors in your stomach that are responsible for triggering acid production. H2 blockers (like PEPCID®) start relieving heartburn symptoms in just 15-30 minutes and control acid for up to 12 hours.
Antacids
Antacids, like Tums®, are intended to treat unexpected heartburn and neutralize the acid in your stomach, but they don’t block production of more acid. Antacids work quickly, but effects may last up to 2 hours per dose.
Proton Pump Inhibitors (PPIs)
PPIs, like Nexium® and Prilosec®, work by shutting down pumps that release acid into your stomach. PPIs require a 14-day regimen, are intended to treat frequent heartburn, and are not intended for immediate relief. In fact, PPIs may take 1-4 days to fully work*. For consistent heartburn relief you’ll need to keep an even more consistent dosing schedule.
*Some consumers will experience complete relief in 24 hours.
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Compare H2 Blocker (PEPCID®) vs. Antacid vs. PPI
PEPCID® is an FDA approved, safe and effective remedy to relieve symptoms of occasional heartburn when used as directed.
1. Starts to relieve heartburn in 15-30 minutes
2. Starts to neutralize acid on contact
3. Prevents heartburn if taken 15-60 minutes before a meal
4. Based on 9 hour acid control studies during the day and 12 hour acid control studies at night. Acid control does not imply symptom relief.
© McNeil Consumer Pharmaceuticals 2021
Third party trademarks used herein are trademarks of their respective owners.
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What Is PEPCID®?
PEPCID® is the original brand with the active ingredient famotidine which is a histamine-2 blocker (H2 blocker) that provides relief for occasional heartburn.